| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SHPRH (Internal Region) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS + 0.02% NaN3 |
| Purification: |
Antigen Affinity Purified |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Shprh |
| Gene ID: |
268281 |
| Uniprot ID: |
SHPRH_MOUSE |
| Immunogen Region: |
Internal Region |
| Specificity: |
Reacts with an internal region of the mouse SHPRH protein. 95% sequence identity to rat. 90% sequence identity to human |
| Immunogen: |
Synthetic peptide corresponding to amino acids from an internal region of mouse SHPRH protein |
| Function | E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'. |
| Protein Name | E3 Ubiquitin-Protein Ligase ShprhRing-Type E3 Ubiquitin Transferase ShprhSnf2 - Histone-Linker - Phd And Ring Finger Domain-Containing Helicase |
| Database Links | Reactome: R-MMU-8866654 |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Shprh antibodyAnti-Ring-Type E3 Ubiquitin Transferase Shprh antibodyAnti-Snf2 - Histone-Linker - Phd And Ring Finger Domain-Containing Helicase antibodyAnti-Shprh antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
