| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SH3KBP1-binding protein 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SHKBP1 |
| Gene ID: |
92799 |
| Uniprot ID: |
SHKB1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of SHKBP1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human SHKBP1 |
| Function | Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation. |
| Protein Name | Sh3kbp1-Binding Protein 1Seta-Binding Protein 1 |
| Database Links | Reactome: R-HSA-9013148 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Sh3kbp1-Binding Protein 1 antibodyAnti-Seta-Binding Protein 1 antibodyAnti-SHKBP1 antibodyAnti-SB1 antibodyAnti-PP203 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
