Anti-SHC2 antibody (261-310 aa) (STJ95587)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SHC2 at the amino acid range 261-310
General Information
| Short Description | Rabbit polyclonal anti-SHC-transforming protein 2 (261-310 aa) for use in WB and IHC in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SHC2 |
| Gene ID | 25759 |
| Uniprot ID | SHC2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human SHC2 at the amino acid range 261-310 |
| Immunogen Region | 261-310 aa |
| Specificity | Sck Polyclonal Antibody detects endogenous levels of Sck protein. |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosines by the Trk receptors. |
| Function | Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. |
| Protein Name | Shc-Transforming Protein 2Protein SckShc-Transforming Protein BSrc Homology 2 Domain-Containing-Transforming Protein C2Sh2 Domain Protein C2 |
| Database Links | Reactome: R-HSA-167044Reactome: R-HSA-4420097Reactome: R-HSA-5673001 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Shc-Transforming Protein 2 antibodyAnti-Protein Sck antibodyAnti-Shc-Transforming Protein B antibodyAnti-Src Homology 2 Domain-Containing-Transforming Protein C2 antibodyAnti-Sh2 Domain Protein C2 antibodyAnti-SHC2 antibodyAnti-SCK antibodyAnti-SHCB antibody |
Information sourced from Uniprot.org