| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SHC-transforming protein 2 (261-310 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SHC2 |
| Gene ID: | 25759 |
| Uniprot ID: | SHC2_HUMAN |
| Immunogen Region: | 261-310 aa |
| Specificity: | Sck Polyclonal Antibody detects endogenous levels of Sck protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SHC2 at the amino acid range 261-310 |
| Post Translational Modifications | Phosphorylated on tyrosines by the Trk receptors. |
| Function | Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. |
| Protein Name | Shc-Transforming Protein 2Protein SckShc-Transforming Protein BSrc Homology 2 Domain-Containing-Transforming Protein C2Sh2 Domain Protein C2 |
| Database Links | Reactome: R-HSA-167044Reactome: R-HSA-4420097Reactome: R-HSA-5673001 |
| Alternative Antibody Names | Anti-Shc-Transforming Protein 2 antibodyAnti-Protein Sck antibodyAnti-Shc-Transforming Protein B antibodyAnti-Src Homology 2 Domain-Containing-Transforming Protein C2 antibodyAnti-Sh2 Domain Protein C2 antibodyAnti-SHC2 antibodyAnti-SCK antibodyAnti-SHCB antibody |
Information sourced from Uniprot.org