| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SHC (425-474) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.55-0.68 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:150 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Shc3 |
| Gene ID: | 20418 |
| Uniprot ID: | SHC3_MOUSE |
| Immunogen Region: | 425-474 |
| Immunogen: | Synthetic peptide taken within amino acid region 425-474 on mouse ShcA protein. |
| Tissue Specificity | Predominantly expressed in the adult brain. |
| Post Translational Modifications | Tyrosine phosphorylated. |
| Function | Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. |
| Protein Name | Shc-Transforming Protein 3Neuronal ShcN-ShcShc-Transforming Protein CSrc Homology 2 Domain-Containing-Transforming Protein C3Sh2 Domain Protein C3 |
| Database Links | Reactome: R-MMU-167044Reactome: -MMU-5673001Reactome: -MMU-8853659 |
| Alternative Antibody Names | Anti-Shc-Transforming Protein 3 antibodyAnti-Neuronal Shc antibodyAnti-N-Shc antibodyAnti-Shc-Transforming Protein C antibodyAnti-Src Homology 2 Domain-Containing-Transforming Protein C3 antibodyAnti-Sh2 Domain Protein C3 antibodyAnti-Shc3 antibodyAnti-Nshc antibodyAnti-ShcC antibody |
Information sourced from Uniprot.org