| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SH2 domain-containing protein 4AA (180-220 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SH2D4A |
| Gene ID: | 63898 |
| Uniprot ID: | SH24A_HUMAN |
| Immunogen Region: | 180-220 aa |
| Specificity: | SH2D4A Polyclonal Antibody detects endogenous levels of SH2D4A protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SH2D4A at the amino acid range 180-220 |
| Function | Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. |
| Protein Name | Sh2 Domain-Containing Protein 4aProtein Sh(2aProtein Phosphatase 1 Regulatory Subunit 38 |
| Cellular Localisation | CytoplasmLocated At Podocyte Foot Processes |
| Alternative Antibody Names | Anti-Sh2 Domain-Containing Protein 4a antibodyAnti-Protein Sh(2a antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 38 antibodyAnti-SH2D4A antibodyAnti-PPP1R38 antibodyAnti-SH2A antibody |
Information sourced from Uniprot.org