• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using SGOL2 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-SGO2 antibody (681-730 aa) (STJ95641)

SKU:
STJ95641

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Shugoshin 2 (681-730 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SGO2
Gene ID: 151246
Uniprot ID: SGO2_HUMAN
Immunogen Region: 681-730 aa
Specificity: Sgo2 Polyclonal Antibody detects endogenous levels of Sgo2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SGOL2 at the amino acid range 681-730
Protein Name Shugoshin 2
Shugoshin-2
Shugoshin-Like 2
Tripin
Database Links Reactome: R-HSA-141444
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-5663220
Reactome: R-HSA-68877
Reactome: R-HSA-9648025
Cellular Localisation Nucleus
Chromosome
Centromere
Kinetochore
During Meiosis I
Accumulates At Centromeres During Diplotene
And Colocalizes Differentially With The Cohesin Subunits Rad21 And Rec8 At Metaphase I Centromeres
Sgo2 And Rad21 Change Their Relative Distributions During Telophase I When Sister-Kinetochore Association Is Lost
During Meiosis Ii
It Shows A Striking Tension-Dependent Redistribution Within Centromeres Throughout Chromosome Congression During Prometaphase Ii
As It Does During Mitosis
In Hela Cells
Localizes At Centromeres Throughout Prophase Until Metaphase And Disappears At Anaphase
Centromeric Localization Requires The Presence Of Bub1 And Aukrb
Alternative Antibody Names Anti-Shugoshin 2 antibody
Anti-Shugoshin-2 antibody
Anti-Shugoshin-Like 2 antibody
Anti-Tripin antibody
Anti-SGO2 antibody
Anti-SGOL2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance