Anti-SGK2 antibody (377-427) {FITC} (STJ502983)

Name: Anti-SGK2 antibody (377-427) {FITC} (STJ502983)
SKU: STJ502983-100
Price: 497.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostChicken

ConjugationFITC

IsotypeIgY

ImmunogenSynthetic peptide taken within amino acid region 377-427 on human Sgk2 protein.

STJ502983-100

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Short Description	Chicken polyclonal antibody anti-SGK2 (377-427) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Applications	ELISA/IHC/IP/WB
Host	Chicken
Reactivity	Human/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgY
Conjugation	FITC
Concentration	0.6 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100 IF: 1:100
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	SGK2
Gene ID	10110
Uniprot ID	SGK2_HUMAN
Immunogen	Synthetic peptide taken within amino acid region 377-427 on human Sgk2 protein.
Immunogen Region	377-427

Tissue Specificity	Highly expressed in liver, kidney and pancreas, and at lower levels in brain.
Post Translational Modifications	Activated by phosphorylation on Ser-356 by an unknown kinase (may be mTORC2 but not confirmed), transforming it into a substrate for PDPK1 which then phosphorylates it on Thr-193.
Function	Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.
Protein Name	Serine/Threonine-Protein Kinase Sgk2 Serum/Glucocorticoid-Regulated Kinase 2
Database Links	Reactome: R-HSA-2672351
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-Serine/Threonine-Protein Kinase Sgk2 antibody Anti-Serum/Glucocorticoid-Regulated Kinase 2 antibody Anti-SGK2 antibody

Information sourced from Uniprot.org