Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SGCD (61-290) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SGCD |
Gene ID: |
6444 |
Uniprot ID: |
SGCD_HUMAN |
Immunogen Region: |
61-290 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 61-290 of human Delta-sarcoglycan (Delta-sarcoglycan (SGCD) ) (NP_000328.2). |
Immunogen Sequence: |
NFTIDGMGNLRITEKGLKLE GDSEFLQPLYAKEIQSRPGN ALYFKSARNVTVNILNDQTK VLTQLITGPKAVEAYGKKFE VKTVSGKLLFSADNNEVVVG AERLRVLGAEGTVFPKSIET PNVRADPFKELRLESPTRSL VMEAPKGVEINAEAGNMEAT CRTELRLESKDGEIKLDAAK IRLPRLPHGSYTPTGTRQKV FEICVCANGRLFLSQAGAGS TCQINTSVCL |
Tissue Specificity | Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung. |
Post Translational Modifications | Glycosylated. Disulfide bonds are present. |
Function | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
Protein Name | Delta-SarcoglycanDelta-Sg35 Kda Dystrophin-Associated Glycoprotein35dag |
Cellular Localisation | Cell MembraneSarcolemmaSingle-Pass Type Ii Membrane ProteinCytoplasmCytoskeleton |
Alternative Antibody Names | Anti-Delta-Sarcoglycan antibodyAnti-Delta-Sg antibodyAnti-35 Kda Dystrophin-Associated Glycoprotein antibodyAnti-35dag antibodyAnti-SGCD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance