| Short Description : | Rabbit polyclonal SGCD (61-290) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SGCD |
| Gene ID: | 6444 |
| Uniprot ID: | SGCD_HUMAN |
| Immunogen Region: | 61-290 |
| Immunogen Sequence: | NFTIDGMGNLRITEKGLKLE GDSEFLQPLYAKEIQSRPGN ALYFKSARNVTVNILNDQTK VLTQLITGPKAVEAYGKKFE VKTVSGKLLFSADNNEVVVG AERLRVLGAEGTVFPKSIET PNVRADPFKELRLESPTRSL VMEAPKGVEINAEAGNMEAT CRTELRLESKDGEIKLDAAK IRLPRLPHGSYTPTGTRQKV FEICVCANGRLFLSQAGAGS TCQINTSVCL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 61-290 of human Delta-sarcoglycan (Delta-sarcoglycan (SGCD) ) (NP_000328.2). |
| Tissue Specificity | Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung. |
| Post Translational Modifications | Glycosylated. Disulfide bonds are present. |
| Function | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
| Protein Name | Delta-SarcoglycanDelta-Sg35 Kda Dystrophin-Associated Glycoprotein35dag |
| Database Links | Reactome: R-HSA-9913351 |
| Cellular Localisation | Cell MembraneSarcolemmaSingle-Pass Type Ii Membrane ProteinCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Delta-Sarcoglycan antibodyAnti-Delta-Sg antibodyAnti-35 Kda Dystrophin-Associated Glycoprotein antibodyAnti-35dag antibodyAnti-SGCD antibody |
Information sourced from Uniprot.org
