Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Monoclonal |
Clone ID : | S6MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SGCD |
Gene ID: | 6444 |
Uniprot ID: | SGCD_HUMAN |
Immunogen Region: | 190-289 |
Specificity: | A synthetic peptide corresponding to a sequence within amino acids 190-289 of human Delta-sarcoglycan (SGCD) (Q92629). |
Immunogen Sequence: | LRLESPTRSLVMEAPKGVEI NAEAGNMEATCRTELRLESK DGEIKLDAAKIRLPRLPHGS YTPTGTRQKVFEICVCANGR LFLSQAGAGSTCQINTSVCL |
Tissue Specificity | Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung. |
Post Translational Modifications | Glycosylated. Disulfide bonds are present. |
Function | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
Protein Name | Delta-SarcoglycanDelta-Sg35 Kda Dystrophin-Associated Glycoprotein35dag |
Cellular Localisation | Cell MembraneSarcolemmaSingle-Pass Type Ii Membrane ProteinCytoplasmCytoskeleton |
Alternative Antibody Names | Anti-Delta-Sarcoglycan antibodyAnti-Delta-Sg antibodyAnti-35 Kda Dystrophin-Associated Glycoprotein antibodyAnti-35dag antibodyAnti-SGCD antibody |
Information sourced from Uniprot.org