| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SGCB |
| Gene ID: | 6443 |
| Uniprot ID: | SGCB_HUMAN |
| Immunogen Region: | 94-318 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 94-318 of human SGCB (NP_000223.1). |
| Immunogen Sequence: | PNGCDSMEFHESGLLRFKQV SDMGVIHPLYKSTVGGRRNE NLVITGNNQPIVFQQGTTKL SVENNKTSITSDIGMQFFDP RTQNILFSTDYETHEFHLPS GVKSLNVQKASTERITSNAT SDLNIKVDGRAIVRGNEGVF IMGKTIEFHMGGNMELKAEN SIILNGSVMVSTTRLPSSSS GDQLGSGDWVRYKLCMCADG TLFKVQVTSQNMGCQISDNP CGNTH |
| Tissue Specificity | Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver. |
| Post Translational Modifications | Disulfide bonds are present. |
| Function | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
| Protein Name | Beta-SarcoglycanBeta-Sg43 Kda Dystrophin-Associated Glycoprotein43dagA3b |
| Cellular Localisation | Cell MembraneSarcolemmaSingle-Pass Type Ii Membrane ProteinCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Beta-Sarcoglycan antibodyAnti-Beta-Sg antibodyAnti-43 Kda Dystrophin-Associated Glycoprotein antibodyAnti-43dag antibodyAnti-A3b antibodyAnti-SGCB antibody |
Information sourced from Uniprot.org