| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SFXN3 |
| Gene ID: | 81855 |
| Uniprot ID: | SFXN3_HUMAN |
| Immunogen Region: | 1-80 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human SFXN3 (NP_112233.2). |
| Immunogen Sequence: | MESKMGELPLDINIQEPRWD QSTFLGRARHFFTVTDPRNL LLSGAQLEASRNIVQNYRAG VVTPGITEDQLWRAKYVYDS |
| Function | Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. |
| Protein Name | Sideroflexin-3 |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sideroflexin-3 antibodyAnti-SFXN3 antibody |
Information sourced from Uniprot.org