| Host: |
Alpaca |
| Applications: |
ELISA/FuncS |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Alpaca monoclonal nanobody anti-Albumin is suitable for use in ELISA and FuncS research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
ALB8 |
| Conjugation: |
Unconjugated |
| Isotype: |
VHH-8His-Cys-tag |
| Formulation: |
0.01M PBS, pH 7.4. |
| Purification: |
Purified by Nickel column. |
| Concentration: |
1.5 mg/mL |
| Storage Instruction: |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
| Post Translational Modifications | Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606. Glycated in diabetic patients. Phosphorylated by FAM20C in the extracellular medium. Acetylated on Lys-223 by acetylsalicylic acid. |
| Function | Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin. |
| Protein Name | Albumin |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-159418Reactome: R-HSA-189451Reactome: R-HSA-189483Reactome: R-HSA-2168880Reactome: R-HSA-381426Reactome: R-HSA-8957275Reactome: R-HSA-8964058Reactome: R-HSA-9707564Reactome: R-HSA-9749641Reactome: R-HSA-9757110Reactome: R-HSA-9793528 |
| Cellular Localisation | Secreted |
| Alternative Nanobody Names | Anti-Albumin nanobodyAnti-ALB nanobodyAnti-GIG20 nanobodyAnti-GIG42 nanobodyAnti-PRO0903 nanobodyAnti-PRO1708 nanobodyAnti-PRO2044 nanobodyAnti-PRO2619 nanobodyAnti-PRO2675 nanobodyAnti-UNQ696 nanobodyAnti-PRO1341 nanobody |
Information sourced from Uniprot.org
![Anti-Serum Albumin/HSA nanobody [ALB8] (STJN000585)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/201198/413296/STJN000585-SDS-PAGE-1__16740.1749232774.jpg?c=1 "Anti-Serum Albumin/HSA nanobody [ALB8] (STJN000585)")
![Anti-Serum Albumin/HSA nanobody [ALB8] (STJN000585)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/201198/413296/STJN000585-SDS-PAGE-1__16740.1749232774.jpg?c=1 "Anti-Serum Albumin/HSA nanobody [ALB8] (STJN000585)")
