Anti-SERPINI1 antibody (181-410) (STJ118149)

Name: Anti-SERPINI1 antibody (181-410) (STJ118149)
SKU: STJ118149
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ118149

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Short Description	Rabbit polyclonal SERPINI1 (181-410) antibody for use in WB, IHC-P and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:100 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SERPINI1
Gene ID	5274
Uniprot ID	NEUS_HUMAN
Immunogen Region	181-410
Immunogen Sequence	INAVYFKGNWKSQFRPENTR TFSFTKDDESEVQIPMMYQQ GEFYYGEFSDGSNEAGGIYQ VLEIPYEGDEISMMLVLSRQ EVPLATLEPLVKAQLVEEWA NSVKKQKVEVYLPRFTVEQE IDLKDVLKALGITEIFIKDA NLTGLSDNKEIFLSKAIHKS FLEVNEEGSEAAAVSGMIAI SRMAVLYPQVIVDHPFFFLI RNRRTGTILFMGRVMHPETM NTSGHDFEEL
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 181-410 of human SERPINI1 (NP_005016.1).

Tissue Specificity	Detected in brain cortex and hippocampus pyramidal neurons (at protein level). Detected in cerebrospinal fluid (at protein level). Predominantly expressed in the brain.
Function	Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (Probable).
Protein Name	Neuroserpin Peptidase Inhibitor 12 Pi-12 Serpin I1
Database Links
Cellular Localisation	Secreted Cytoplasmic Vesicle Secretory Vesicle Lumen Perikaryon
Alternative Antibody Names	Anti-Neuroserpin antibody Anti-Peptidase Inhibitor 12 antibody Anti-Pi-12 antibody Anti-Serpin I1 antibody Anti-SERPINI1 antibody Anti-PI12 antibody

Information sourced from Uniprot.org