| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Plasma protease C1 inhibitor (342-391 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SERPING1 |
| Gene ID: | 710 |
| Uniprot ID: | IC1_HUMAN |
| Immunogen Region: | 342-391 aa |
| Specificity: | C1INH Polyclonal Antibody detects endogenous levels of C1INH protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SERPING1 at the amino acid range 342-391 |
| Function | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |
| Protein Name | Plasma Protease C1 InhibitorC1 InhC1inhC1 Esterase InhibitorC1-Inhibiting FactorSerpin G1 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-140837Reactome: R-HSA-9657689Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Plasma Protease C1 Inhibitor antibodyAnti-C1 Inh antibodyAnti-C1inh antibodyAnti-C1 Esterase Inhibitor antibodyAnti-C1-Inhibiting Factor antibodyAnti-Serpin G1 antibodyAnti-SERPING1 antibodyAnti-C1IN antibodyAnti-C1NH antibody |
Information sourced from Uniprot.org
