| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SERPINE2 |
| Gene ID: | 5270 |
| Uniprot ID: | GDN_HUMAN |
| Immunogen Region: | 27-398 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-398 of human SERPINE2 (NP_006207.1). |
| Immunogen Sequence: | LEELGSNTGIQVFNQIVKSR PHDNIVISPHGIASVLGMLQ LGADGRTKKQLAMVMRYGVN GVGKILKKINKAIVSKKNKD IVTVANAVFVKNASEIEVPF VTRNKDVFQCEVRNVNFEDP ASACDSINAWVKNETRDMID NLLSPDLIDGVLTRLVLVNA VYFKGLWKSRFQPENTKKRT FVAADGKSYQVPMLAQLSVF RCGSTSAPNDLWYNFIELPY HGESISMLIALPTESSTPL |
| Function | Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin. |
| Protein Name | Glia-Derived Nexin Gdn Peptidase Inhibitor 7 Pi-7 Protease Nexin 1 Pn-1 Protease Nexin I Serpin E2 |
| Database Links | Reactome: R-HSA-140837 Reactome: R-HSA-140875 Reactome: R-HSA-75205 |
| Cellular Localisation | Secreted Extracellular Space |
| Alternative Antibody Names | Anti-Glia-Derived Nexin antibody Anti-Gdn antibody Anti-Peptidase Inhibitor 7 antibody Anti-Pi-7 antibody Anti-Protease Nexin 1 antibody Anti-Pn-1 antibody Anti-Protease Nexin I antibody Anti-Serpin E2 antibody Anti-SERPINE2 antibody Anti-PI7 antibody Anti-PN1 antibody |
Information sourced from Uniprot.org