| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SERPINA4 |
| Gene ID: | 5267 |
| Uniprot ID: | KAIN_HUMAN |
| Immunogen Region: | 178-427 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 178-427 of human Kallistatin (SERPINA4) (NP_006206.2). |
| Immunogen Sequence: | TIQLINDHVKKETRGKIVDL VSELKKDVLMVLVNYIYFKA LWEKPFISSRTTPKDFYVDE NTTVRVPMMLQDQEHHWYLH DRYLPCSVLRMDYKGDATVF FILPNQGKMREIEEVLTPEM LMRWNNLLRKRNFYKKLELH LPKFSISGSYVLDQILPRLG FTDLFSKWADLSGITKQQKL EASKSFHKATLDVDEAGTEA AAATSFAIKFFSAQTNRHIL RFNRPFLVVIFSTSTQSVL |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. |
| Protein Name | KallistatinKallikrein InhibitorPeptidase Inhibitor 4Pi-4Serpin A4 |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Kallistatin antibodyAnti-Kallikrein Inhibitor antibodyAnti-Peptidase Inhibitor 4 antibodyAnti-Pi-4 antibodyAnti-Serpin A4 antibodyAnti-SERPINA4 antibodyAnti-KST antibodyAnti-PI4 antibody |
Information sourced from Uniprot.org