Host: |
Rabbit |
Applications: |
WB/ELISA/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Septin-8 (170-219 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SEPTIN8 |
Gene ID: |
23176 |
Uniprot ID: |
SEPT8_HUMAN |
Immunogen Region: |
170-219 aa |
Specificity: |
Septin 8 Polyclonal Antibody detects endogenous levels of Septin 8 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human SEPT8 at the amino acid range 170-219 |
Function | Filament-forming cytoskeletal GTPase. May play a role in platelet secretion. Seems to participate in the process of SNARE complex formation in synaptic vesicles. Isoform 4: Stabilizes BACE1 protein levels and promotes the sorting and accumulation of BACE1 to the recycling or endosomal compartments, modulating the beta-amyloidogenic processing of APP. |
Protein Name | Septin-8 |
Cellular Localisation | CytoplasmCytoskeletonSynapseCell ProjectionAxonCytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembranePresynapseExpressed In Axons Of Immature NeuronsLocalizes To Synapses In Mature NeuronsIn PlateletsFound In Areas Surrounding Alpha-Granules |
Alternative Antibody Names | Anti-Septin-8 antibodyAnti-SEPTIN8 antibodyAnti-KIAA0202 antibodyAnti-SEPT8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance