• Western blot analysis of lysates from HeLa cells, using SEPT8 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Septin 8 Polyclonal Antibody diluted at 1:2000

Anti-SEPTIN8 antibody (170-219 aa) (STJ95617)

SKU:
STJ95617

Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Septin-8 (170-219 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SEPTIN8
Gene ID: 23176
Uniprot ID: SEPT8_HUMAN
Immunogen Region: 170-219 aa
Specificity: Septin 8 Polyclonal Antibody detects endogenous levels of Septin 8 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SEPT8 at the amino acid range 170-219
Function Filament-forming cytoskeletal GTPase. May play a role in platelet secretion. Seems to participate in the process of SNARE complex formation in synaptic vesicles. Isoform 4: Stabilizes BACE1 protein levels and promotes the sorting and accumulation of BACE1 to the recycling or endosomal compartments, modulating the beta-amyloidogenic processing of APP.
Protein Name Septin-8
Cellular Localisation Cytoplasm
Cytoskeleton
Synapse
Cell Projection
Axon
Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Presynapse
Expressed In Axons Of Immature Neurons
Localizes To Synapses In Mature Neurons
In Platelets
Found In Areas Surrounding Alpha-Granules
Alternative Antibody Names Anti-Septin-8 antibody
Anti-SEPTIN8 antibody
Anti-KIAA0202 antibody
Anti-SEPT8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance