| Tissue Specificity | Widely expressed. Isoforms are differentially expressed in testes, kidney, liver heart, spleen, brain, peripheral blood leukocytes, skeletal muscle and kidney. Specific isoforms appear to demonstrate tissue specificity. Isoform 5 is the most highly expressed in fetal tissue. Isoform 1 is detected in all tissues except the brain and thymus, while isoform 2, isoform 3, and isoform 4 are detected at low levels in approximately half of the fetal tissues. |
| Function | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri. |
| Protein Name | Septin-9Mll Septin-Like Fusion Protein Msf-AMll Septin-Like Fusion ProteinOvarian/Breast SeptinOv/Br SeptinSeptin D1 |
| Cellular Localisation | CytoplasmCytoskeletonIn An Epithelial Cell LineConcentrates At Cell-Cell Contact AreasAfter Tgf-Beta1 Treatment And Induction Of Epithelial To Mesenchymal TransitionColocalizes Partly With Actin Stress FibersDuring Bacterial InfectionDisplays A Collar Shape Structure Next To Actin At The Pole Of Invading Bacteria |
| Alternative Antibody Names | Anti-Septin-9 antibodyAnti-Mll Septin-Like Fusion Protein Msf-A antibodyAnti-Mll Septin-Like Fusion Protein antibodyAnti-Ovarian/Breast Septin antibodyAnti-Ov/Br Septin antibodyAnti-Septin D1 antibodyAnti-SEPTIN9 antibodyAnti-KIAA0991 antibodyAnti-MSF antibodyAnti-SEPT9 antibody |
Information sourced from Uniprot.org
