| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SEPTIN3 |
| Gene ID: | 55964 |
| Uniprot ID: | SEPT3_HUMAN |
| Immunogen Region: | 179-358 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 179-358 of human Septin 3 (NP_663786.2). |
| Immunogen Sequence: | SPTGHSLRPLDLEFMKHLSK VVNIIPVIAKADTMTLEEKS EFKQRVRKELEVNGIEFYPQ KEFDEDLEDKTENDKIRQES MPFAVVGSDKEYQVNGKRVL GRKTPWGIIEVENLNHCEFA LLRDFVIRTHLQDLKEVTHN IHYETYRAKRLNDNGGLPPG EGLLGTVLPPVPATPCPTAE |
| Tissue Specificity | Brain-specific. |
| Post Translational Modifications | Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91. |
| Function | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). |
| Protein Name | Neuronal-Specific Septin-3 |
| Cellular Localisation | CytoplasmCytoskeletonSynapse |
| Alternative Antibody Names | Anti-Neuronal-Specific Septin-3 antibodyAnti-SEPTIN3 antibodyAnti-SEP3 antibodyAnti-SEPT3 antibody |
Information sourced from Uniprot.org