| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | SEMA6B |
| Gene ID: | 10501 |
| Uniprot ID: | SEM6B_HUMAN |
| Immunogen Region: | 26-170 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-170 of human SEMA6B (NP_115484.2). |
| Immunogen Sequence: | LFPEEPPPLSVAPRDYLNHY PVFVGSGPGRLTPAEGADDL NIQRVLRVNRTLFIGDRDNL YRVELEPPTSTELRYQRKLT WRSNPSDINVCRMKGKQEGE CRNFVKVLLLRDESTLFVCG SNAFNPVCANYSIDTLQPVG DNISG |
| Tissue Specificity | Expressed in the brain in GABAergic neurons. |
| Function | Functions as a cell surface repellent for mossy fibers of developing neurons in the hippocampus where it plays a role in axon guidance. May function through the PLXNA4 receptor expressed by mossy cell axons. (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium. |
| Protein Name | Semaphorin-6bSemaphorin-ZSema Z |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Semaphorin-6b antibodyAnti-Semaphorin-Z antibodyAnti-Sema Z antibodyAnti-SEMA6B antibodyAnti-SEMAN antibodyAnti-SEMAZ antibodyAnti-UNQ1907 antibodyAnti-PRO4353 antibody |
Information sourced from Uniprot.org