| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4751RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:2000-1:20000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SEMA3A |
| Gene ID: | 10371 |
| Uniprot ID: | SEM3A_HUMAN |
| Immunogen Region: | 582-771 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 582-771 of human Semaphorin 3A (NP_006071.1). |
| Immunogen Sequence: | ERIIYGVENSSTFLECSPKS QRALVYWQFQRRNEERKEEI RVDDHIIRTDQGLLLRSLQQ KDSGNYLCHAVEHGFIQTLL KVTLEVIDTEHLEELLHKDD DGDGSKTKEMSNSMTPSQKV WYRDFMQLINHPNLNTMDEF CEQVWKRDRKQRRQRPGHTP GNSNKWKHLQENKKGRNRRT HEFERAPRSV |
| Tissue Specificity | Expressed in the dorsal root ganglia. |
| Function | Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1. |
| Protein Name | Semaphorin-3aSemaphorin IiiSema Iii |
| Database Links | Reactome: R-HSA-399954Reactome: R-HSA-399955Reactome: R-HSA-399956 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Semaphorin-3a antibodyAnti-Semaphorin Iii antibodyAnti-Sema Iii antibodyAnti-SEMA3A antibodyAnti-SEMAD antibody |
Information sourced from Uniprot.org
