Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-P-selectin (81-130 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC-P 1:100-1:300 ELISA 1:10000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SELP |
Gene ID: | 6403 |
Uniprot ID: | LYAM3_HUMAN |
Immunogen Region: | 81-130 aa |
Specificity: | P-Selectin Polyclonal Antibody detects endogenous levels of P-Selectin protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELP at the amino acid range 81-130 |
Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3). |
Protein Name | P-Selectin Cd62 Antigen-Like Family Member P Granule Membrane Protein 140 Gmp-140 Leukocyte-Endothelial Cell Adhesion Molecule 3 Lecam3 Platelet Activation Dependent Granule-External Membrane Protein Padgem Cd Antigen Cd62p |
Database Links | Reactome: R-HSA-114608 Reactome: R-HSA-202733 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-P-Selectin antibody Anti-Cd62 Antigen-Like Family Member P antibody Anti-Granule Membrane Protein 140 antibody Anti-Gmp-140 antibody Anti-Leukocyte-Endothelial Cell Adhesion Molecule 3 antibody Anti-Lecam3 antibody Anti-Platelet Activation Dependent Granule-External Membrane Protein antibody Anti-Padgem antibody Anti-Cd Antigen Cd62p antibody Anti-SELP antibody Anti-GMRP antibody Anti-GRMP antibody |
Information sourced from Uniprot.org