Anti-SELL antibody (56-69) (STJ25469)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SELL (56-69) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SELL |
| Gene ID | 6402 |
| Uniprot ID | LYAM1_HUMAN |
| Immunogen Region | 56-69 |
| Immunogen Sequence | MIFPWKCQSTQRDLWNIFKL WGWTMLCCDFLAHHGTDCWT YHYSEKPMNWQRARRFCRDN YTDLVAIQNKAEIEYLEKTL PFSRSYYWIGIRKIGGIWTW |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD62L/L-Selectin (NP_000646.2). |
Additional Info
| Tissue Specificity | Expressed in B-cell lines and T-lymphocytes. |
| Post Translational Modifications | N-glycosylated. |
| Function | Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. |
| Protein Name | L-SelectinCd62 Antigen-Like Family Member LLeukocyte Adhesion Molecule 1Lam-1Leukocyte Surface Antigen Leu-8Leukocyte-Endothelial Cell Adhesion Molecule 1Lecam1Lymph Node Homing ReceptorTq1Gp90-MelCd Antigen Cd62l |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-L-Selectin antibodyAnti-Cd62 Antigen-Like Family Member L antibodyAnti-Leukocyte Adhesion Molecule 1 antibodyAnti-Lam-1 antibodyAnti-Leukocyte Surface Antigen Leu-8 antibodyAnti-Leukocyte-Endothelial Cell Adhesion Molecule 1 antibodyAnti-Lecam1 antibodyAnti-Lymph Node Homing Receptor antibodyAnti-Tq1 antibodyAnti-Gp90-Mel antibodyAnti-Cd Antigen Cd62l antibodyAnti-SELL antibodyAnti-LNHR antibodyAnti-LYAM1 antibody |
Information sourced from Uniprot.org