Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SELL (56-69) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SELL |
Gene ID: |
6402 |
Uniprot ID: |
LYAM1_HUMAN |
Immunogen Region: |
56-69 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 56-69 of human CD62L/L-Selectin (NP_000646.2). |
Immunogen Sequence: |
YSEKPMNWQRARRF |
Tissue Specificity | Expressed in B-cell lines and T-lymphocytes. |
Post Translational Modifications | N-glycosylated. |
Function | Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. |
Protein Name | L-SelectinCd62 Antigen-Like Family Member LLeukocyte Adhesion Molecule 1Lam-1Leukocyte Surface Antigen Leu-8Leukocyte-Endothelial Cell Adhesion Molecule 1Lecam1Lymph Node Homing ReceptorTq1Gp90-MelCd Antigen Cd62l |
Database Links | Reactome: R-HSA-198933Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-L-Selectin antibodyAnti-Cd62 Antigen-Like Family Member L antibodyAnti-Leukocyte Adhesion Molecule 1 antibodyAnti-Lam-1 antibodyAnti-Leukocyte Surface Antigen Leu-8 antibodyAnti-Leukocyte-Endothelial Cell Adhesion Molecule 1 antibodyAnti-Lecam1 antibodyAnti-Lymph Node Homing Receptor antibodyAnti-Tq1 antibodyAnti-Gp90-Mel antibodyAnti-Cd Antigen Cd62l antibodyAnti-SELL antibodyAnti-LNHR antibodyAnti-LYAM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance