• Western blot analysis of lysates from Mouse kidney using SELENBP1 Rabbit polyclonal antibody (STJ11104553) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25  Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SELENBP1 antibody (243-472) (STJ11104553)

SKU:
STJ11104553

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Methanethiol Oxidase (243-472) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SELENBP1
Gene ID: 8991
Uniprot ID: SBP1_HUMAN
Immunogen Region: 243-472
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 243-472 of human SELENBP1 (NP_003935.2).
Immunogen Sequence: SLKDGLIPLEIRFLHNPDAA QGFVGCALSSTIQRFYKNEG GTWSVEKVIQVPPKKVKGWL LPEMPGLITDILLSLDDRFL YFSNWLHGDLRQYDISDPQR PRLTGQLFLGGSIVKGGPVQ VLEDEELKSQPEPLVVKGKR VAGGPQMIQLSLDGKRLYIT TSLYSAWDKQFYPDLIREGS VMLQVDVDTVKGGLKLNPNF LVDFGKEPLGPALAHELRYP GGDCSSDIWI
Tissue Specificity Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients.
Post Translational Modifications Phosphorylated. The N-terminus is blocked.
Function Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
Protein Name Methanethiol Oxidase
Mto
56 Kda Selenium-Binding Protein
Sbp56
Sp56
Selenium-Binding Protein 1
Cellular Localisation Nucleus
Cytoplasm
Cytosol
Membrane
Peripheral Membrane Protein
May Associate With Golgi Membrane
May Associate With The Membrane Of Autophagosomes
Alternative Antibody Names Anti-Methanethiol Oxidase antibody
Anti-Mto antibody
Anti-56 Kda Selenium-Binding Protein antibody
Anti-Sbp56 antibody
Anti-Sp56 antibody
Anti-Selenium-Binding Protein 1 antibody
Anti-SELENBP1 antibody
Anti-SBP antibody

Information sourced from Uniprot.org

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