| Short Description : | Rabbit polyclonal Methanethiol Oxidase (243-472) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SELENBP1 |
| Gene ID: | 8991 |
| Uniprot ID: | SBP1_HUMAN |
| Immunogen Region: | 243-472 |
| Immunogen Sequence: | SLKDGLIPLEIRFLHNPDAA QGFVGCALSSTIQRFYKNEG GTWSVEKVIQVPPKKVKGWL LPEMPGLITDILLSLDDRFL YFSNWLHGDLRQYDISDPQR PRLTGQLFLGGSIVKGGPVQ VLEDEELKSQPEPLVVKGKR VAGGPQMIQLSLDGKRLYIT TSLYSAWDKQFYPDLIREGS VMLQVDVDTVKGGLKLNPNF LVDFGKEPLGPALAHELRYP GGDCSSDIWI |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 243-472 of human SELENBP1 (NP_003935.2). |
| Tissue Specificity | Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients. |
| Post Translational Modifications | Phosphorylated. The N-terminus is blocked. |
| Function | Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport. |
| Protein Name | Methanethiol OxidaseMto56 Kda Selenium-Binding ProteinSbp56Sp56Selenium-Binding Protein 1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytosolMembranePeripheral Membrane ProteinMay Associate With Golgi MembraneMay Associate With The Membrane Of Autophagosomes |
| Alternative Antibody Names | Anti-Methanethiol Oxidase antibodyAnti-Mto antibodyAnti-56 Kda Selenium-Binding Protein antibodyAnti-Sbp56 antibodyAnti-Sp56 antibodyAnti-Selenium-Binding Protein 1 antibodyAnti-SELENBP1 antibodyAnti-SBP antibody |
Information sourced from Uniprot.org
