| Tissue Specificity | Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients. |
| Post Translational Modifications | Phosphorylated. The N-terminus is blocked. |
| Function | Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport. |
| Protein Name | Methanethiol OxidaseMto56 Kda Selenium-Binding ProteinSbp56Sp56Selenium-Binding Protein 1 |
| Cellular Localisation | NucleusCytoplasmCytosolMembranePeripheral Membrane ProteinMay Associate With Golgi MembraneMay Associate With The Membrane Of Autophagosomes |
| Alternative Antibody Names | Anti-Methanethiol Oxidase antibodyAnti-Mto antibodyAnti-56 Kda Selenium-Binding Protein antibodyAnti-Sbp56 antibodyAnti-Sp56 antibodyAnti-Selenium-Binding Protein 1 antibodyAnti-SELENBP1 antibodyAnti-SBP antibody |
Information sourced from Uniprot.org
