| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | D.melanogaster/Human/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SEC23A (700-765) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.65 µg/µl |
| Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:350 IHC: 1:100 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | SEC23A |
| Gene ID: | 10484 |
| Uniprot ID: | SC23A_HUMAN |
| Immunogen Region: | 700-765 |
| Specificity: | This antibody will label both SEC23A and SEC23B in human protein. |
| Immunogen: | Synthetic peptide taken within amino acid region 700-765 on human SEC23A protein. |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane. |
| Protein Name | Protein Transport Protein Sec23a Hsec23a Sec23-Related Protein A |
| Database Links | Reactome: R-HSA-1655829 Reactome: R-HSA-204005 Reactome: R-HSA-2132295 Reactome: R-HSA-5694530 Reactome: R-HSA-9705671 Reactome: R-HSA-983170 |
| Cellular Localisation | Cytoplasmic Vesicle Copii-Coated Vesicle Membrane Peripheral Membrane Protein Cytoplasmic Side Endoplasmic Reticulum Membrane Cytoplasm Cytosol Enriched At Endoplasmic Reticulum Exit Sites Also Known As Transitional Endoplasmic Reticulum (Ter) |
| Alternative Antibody Names | Anti-Protein Transport Protein Sec23a antibody Anti-Hsec23a antibody Anti-Sec23-Related Protein A antibody Anti-SEC23A antibody |
Information sourced from Uniprot.org