| Function | Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids. |
| Protein Name | Signal Peptidase Complex Catalytic Subunit Sec11aEndopeptidase Sp18Microsomal Signal Peptidase 18 Kda SubunitSpase 18 Kda SubunitSec11 Homolog ASec11-Like Protein 1Spc18 |
| Database Links | Reactome: R-HSA-1799339Reactome: R-HSA-381771Reactome: R-HSA-400511Reactome: R-HSA-422085Reactome: R-HSA-9828806 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Signal Peptidase Complex Catalytic Subunit Sec11a antibodyAnti-Endopeptidase Sp18 antibodyAnti-Microsomal Signal Peptidase 18 Kda Subunit antibodyAnti-Spase 18 Kda Subunit antibodyAnti-Sec11 Homolog A antibodyAnti-Sec11-Like Protein 1 antibodyAnti-Spc18 antibodyAnti-SEC11A antibodyAnti-SEC11L1 antibodyAnti-SPC18 antibodyAnti-SPCS4A antibody |
Information sourced from Uniprot.org
