Anti-SDHB antibody [BP6160] (STJA0037685)

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STJA0037685-50
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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-SDHB for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : BP6160
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification: Affinity Purified
Dilution Range: IHC 1:100-1:200
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: SDHB
Gene ID: 6390
Uniprot ID: SDHB_HUMAN
Immunogen: A synthesized peptide derived from human SDHB
Function Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate.
Protein Name Succinate Dehydrogenase Ubiquinone Iron-Sulfur Subunit - Mitochondrial
Iron-Sulfur Subunit Of Complex Ii
Ip
Malate Dehydrogenase Quinone Iron-Sulfur Subunit
Database Links Reactome: R-HSA-611105
Reactome: R-HSA-71403
Reactome: R-HSA-9854311
Cellular Localisation Mitochondrion Inner Membrane
Peripheral Membrane Protein
Matrix Side
Alternative Antibody Names Anti-Succinate Dehydrogenase Ubiquinone Iron-Sulfur Subunit - Mitochondrial antibody
Anti-Iron-Sulfur Subunit Of Complex Ii antibody
Anti-Ip antibody
Anti-Malate Dehydrogenase Quinone Iron-Sulfur Subunit antibody
Anti-SDHB antibody
Anti-SDH antibody
Anti-SDH1 antibody

Information sourced from Uniprot.org