Anti-SDCCAG8 antibody (469-483) (STJ72780)

SKU:
STJ72780-100

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Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-SDCCAG8 (469-483) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-5µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SDCCAG8
Gene ID: 10806
Uniprot ID: SDCG8_HUMAN
Immunogen Region: 469-483
Accession Number: NP_006633.1
Immunogen Sequence: DEAEKEHREFRAKTN
Function Plays a role in the establishment of cell polarity and epithelial lumen formation. Also plays an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis.
Protein Name Serologically Defined Colon Cancer Antigen 8
Antigen Ny-Co-8
Centrosomal Colon Cancer Autoantigen Protein
Hcccap
Database Links Reactome: R-HSA-2565942
Reactome: R-HSA-380259
Reactome: R-HSA-380270
Reactome: R-HSA-380284
Reactome: R-HSA-380320
Reactome: R-HSA-5620912
Reactome: R-HSA-8854518
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Centriole
Cilium Basal Body
Cell Junction
Located At The Distal Ends Of Both Centrioles And Colocalizes To Centrosomes Throughout The Cell Cycle
Isoform 2: Cytoplasm
Alternative Antibody Names Anti-Serologically Defined Colon Cancer Antigen 8 antibody
Anti-Antigen Ny-Co-8 antibody
Anti-Centrosomal Colon Cancer Autoantigen Protein antibody
Anti-Hcccap antibody
Anti-SDCCAG8 antibody
Anti-CCCAP antibody
Anti-NPHP10 antibody
Anti-HSPC085 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance