Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SCO2 (100-266) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SCO2 |
Gene ID: |
9997 |
Uniprot ID: |
SCO2_HUMAN |
Immunogen Region: |
100-266 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 100-266 of human SCO2 (NP_005129.2). |
Immunogen Sequence: |
GQGDFHLLDHRGRARCKADF RGQWVLMYFGFTHCPDICPD ELEKLVQVVRQLEAEPGLPP VQPVFITVDPERDDVEAMAR YVQDFHPRLLGLTGSTKQVA QASHSYRVYYNAGPKDEDQD YIVDHSIAIYLLNPDGLFTD YYGRSRSAEQISDSVRRHMA AFRSVLS |
Tissue Specificity | Ubiquitous. |
Function | Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2. |
Protein Name | Protein Sco2 Homolog - Mitochondrial |
Database Links | Reactome: R-HSA-5628897Reactome: R-HSA-611105Reactome: R-HSA-9707564 |
Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
Alternative Antibody Names | Anti-Protein Sco2 Homolog - Mitochondrial antibodyAnti-SCO2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance