• Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-SCO1 antibody (223-273 aa) (STJ194085)

SKU:
STJ194085

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Protein SCO1 homolog, mitochondrial (223-273 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SCO1
Gene ID: 6341
Uniprot ID: SCO1_HUMAN
Immunogen Region: 223-273 aa
Specificity: This antibody detects endogenous levels of SCO1 at Human/Mouse
Immunogen: Synthesized peptide derived from the human SCO1 at the amino acid range 223-273
Function Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1.
Protein Name Protein Sco1 Homolog - Mitochondrial
Database Links Reactome: R-HSA-5628897
Reactome: R-HSA-611105
Reactome: R-HSA-9707564
Cellular Localisation Mitochondrion
Mitochondrion Inner Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Protein Sco1 Homolog - Mitochondrial antibody
Anti-SCO1 antibody
Anti-SCOD1 antibody

Information sourced from Uniprot.org

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