| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein SCO1 homolog, mitochondrial (223-273 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SCO1 |
| Gene ID: | 6341 |
| Uniprot ID: | SCO1_HUMAN |
| Immunogen Region: | 223-273 aa |
| Specificity: | This antibody detects endogenous levels of SCO1 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human SCO1 at the amino acid range 223-273 |
| Function | Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1. |
| Protein Name | Protein Sco1 Homolog - Mitochondrial |
| Database Links | Reactome: R-HSA-9864848 |
| Cellular Localisation | MitochondrionMitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein Sco1 Homolog - Mitochondrial antibodyAnti-SCO1 antibodyAnti-SCOD1 antibody |
Information sourced from Uniprot.org