Anti-SCNN1D antibody (411-460 aa) (STJ92917)

SKU:
STJ92917
£48.00 - £252.00
Processing The item has been added

Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Amiloride-sensitive sodium channel subunit delta channel subunit delta (411-460 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SCNN1D
Gene ID: 6339
Uniprot ID: SCNND_HUMAN
Immunogen Region: 411-460 aa
Specificity: ENaC Delta Polyclonal Antibody detects endogenous levels of ENaC Delta protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SCNN1D at the amino acid range 411-460
Function Potential alternative pore-forming subunit of the epithelial sodium channel (ENaC), capable of replacing the alpha/SCNN1A subunit, creating a more active channel with distinct properties. ENaC functions in epithelial tissues, where it facilitates the electrodiffusion of sodium ions from the extracellular fluid through the apical membrane of cells, with water following osmotically, regulating sodium balance and fluid homeostasis. This subunit could also function independently as a sodium channel or assemble into other tissue-specific heterotrimeric sodium channels. Isoform 2: ENaC channels including this isoform exhibit greater conductance.
Protein Name Epithelial Sodium Channel Subunit Delta
Delta-Enac
Enacd
Epithelial Na(+ Channel Subunit Delta
Amiloride-Sensitive Sodium Channel Subunit Delta
Delta-Nach
Nonvoltage-Gated Sodium Channel 1 Subunit Delta
Scned
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-9730628
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Epithelial Sodium Channel Subunit Delta antibody
Anti-Delta-Enac antibody
Anti-Enacd antibody
Anti-Epithelial Na(+ Channel Subunit Delta antibody
Anti-Amiloride-Sensitive Sodium Channel Subunit Delta antibody
Anti-Delta-Nach antibody
Anti-Nonvoltage-Gated Sodium Channel 1 Subunit Delta antibody
Anti-Scned antibody
Anti-SCNN1D antibody
Anti-DNACH antibody

Information sourced from Uniprot.org