| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Sodium channel protein type 11 subunit alpha is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SCN11A |
| Gene ID: |
11280 |
| Uniprot ID: |
SCNBA_HUMAN |
| Specificity: |
SCNBA Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Sodium channel mediating the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Involved in membrane depolarization during action potential in nociceptors which function as key relay stations for the electrical transmission of pain signals from the periphery to the central nervous system. Also involved in rapid BDNF-evoked neuronal depolarization. |
| Protein Name | Sodium Channel Protein Type 11 Subunit AlphaPeripheral Nerve Sodium Channel 5Pn5Sensory Neuron Sodium Channel 2Sodium Channel Protein Type Xi Subunit AlphaVoltage-Gated Sodium Channel Subunit Alpha Nav1.9Hnan |
| Database Links | Reactome: R-HSA-445095Reactome: R-HSA-5576892 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium Channel Protein Type 11 Subunit Alpha antibodyAnti-Peripheral Nerve Sodium Channel 5 antibodyAnti-Pn5 antibodyAnti-Sensory Neuron Sodium Channel 2 antibodyAnti-Sodium Channel Protein Type Xi Subunit Alpha antibodyAnti-Voltage-Gated Sodium Channel Subunit Alpha Nav1.9 antibodyAnti-Hnan antibodyAnti-SCN11A antibodyAnti-SCN12A antibodyAnti-SNS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
