| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SCGN |
| Gene ID: | 10590 |
| Uniprot ID: | SEGN_HUMAN |
| Immunogen Region: | 1-276 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-276 of human Secretagogin (Secretagogin (SCGN) ) (NP_008929.2). |
| Immunogen Sequence: | MDSSREPTLGRLDAAGFWQV WQRFDADEKGYIEEKELDAF FLHMLMKLGTDDTVMKANLH KVKQQFMTTQDASKDGRIRM KELAGMFLSEDENFLLLFRR ENPLDSSVEFMQIWRKYDAD SSGFISAAELRNFLRDLFLH HKKAISEAKLEEYTGTMMKI FDRNKDGRLDLNDLARILAL QENFLLQFKMDACSTEERKR DFEKIFAYYDVSKTGALEGP EVDGFVKDMMELVQPSISG |
| Tissue Specificity | Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons. |
| Protein Name | Secretagogin |
| Cellular Localisation | CytoplasmSecretedCytoplasmic VesicleSecretory Vesicle MembranePeripheral Membrane ProteinCytoplasmic SidePredominantly CytoplasmicA Small Proportion Is Associated With Secretory Granules And Membrane FractionsDetectable In Human Serum After Ischemic Neuronal Damage |
| Alternative Antibody Names | Anti-Secretagogin antibodyAnti-SCGN antibodyAnti-SECRET antibody |
Information sourced from Uniprot.org