Anti-SCG3 antibody [SAA1746] (STJA0020174)

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STJA0020174
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Short Description :Mouse monoclonal Secretogranin-3 antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Clonality :Monoclonal
Clone ID :SAA1746
Isotype:IgG2a
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Protein A/G purified from cell culture supernatant
Formulation:0.01M PBS, pH 7.4.
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol:SCG3
Gene ID:29106
Uniprot ID:SCG3_HUMAN
Post Translational Modifications O-glycosylated.
Function Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway.
Protein Name Secretogranin-3
Secretogranin Iii
Sgiii
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle
Secretory Vesicle Membrane
Peripheral Membrane Protein
Secreted
Associated With The Secretory Granule Membrane Through Direct Binding To Cholesterol-Enriched Lipid Rafts
Alternative Antibody Names Anti-Secretogranin-3 antibody
Anti-Secretogranin Iii antibody
Anti-Sgiii antibody
Anti-SCG3 antibody
Anti-UNQ2502 antibody
Anti-PRO5990 antibody

Information sourced from Uniprot.org