| Tissue Specificity | Detected in fetal liver, lung and brain. Highly expressed in adult adipose tissue, and at lower levels in adult brain and lung. |
| Function | Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation. Plays an important role in body energy homeostasis. Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides. |
| Protein Name | Stearoyl-Coa DesaturaseHscd1Acyl-Coa DesaturaseDelta(9-DesaturaseDelta-9 DesaturaseFatty Acid Desaturase |
| Database Links | Reactome: R-HSA-2426168Reactome: R-HSA-75105Reactome: R-HSA-9029558Reactome: R-HSA-9841922 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Stearoyl-Coa Desaturase antibodyAnti-Hscd1 antibodyAnti-Acyl-Coa Desaturase antibodyAnti-Delta(9-Desaturase antibodyAnti-Delta-9 Desaturase antibodyAnti-Fatty Acid Desaturase antibodyAnti-SCD antibodyAnti-FADS5 antibodyAnti-SCD1 antibodyAnti-SCDOS antibody |
Information sourced from Uniprot.org
