alpha actinin 2 antibody western blot human skeletal muscle STJA0037035

Anti-Sarcomeric alpha Actinin antibody [R04-4U7] (STJA0037035)

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STJA0037035
£133.50 - £281.50
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Short Description :Rabbit monoclonal anti-Sarcomeric alpha Actinin for use in WB, IHC-P and IP in Mouse, Rat and Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/IP
Host:Rabbit
Reactivity:Mouse/Rat/Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R04-4U7
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
IP 1:30
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:ACTN2
Gene ID:88
Uniprot ID:ACTN2_HUMAN
Immunogen:A synthesized peptide derived from human Alpha actinin 2
Tissue Specificity Expressed in both skeletal and cardiac muscle.
Post Translational Modifications Ubiquitinated by FBXL22, leading to proteasomal degradation.
Function F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Protein Name Alpha-Actinin-2
Alpha-Actinin Skeletal Muscle Isoform 2
F-Actin Cross-Linking Protein
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-373753
Reactome: R-HSA-390522
Reactome: R-HSA-438066
Reactome: R-HSA-442982
Reactome: R-HSA-5673001
Reactome: R-HSA-9609736
Reactome: R-HSA-9617324
Reactome: R-HSA-9620244
Cellular Localisation Cytoplasm
Myofibril
Sarcomere
Z Line
Colocalizes With Myoz1 And Flnc At The Z-Lines Of Skeletal Muscle
Alternative Antibody Names Anti-Alpha-Actinin-2 antibody
Anti-Alpha-Actinin Skeletal Muscle Isoform 2 antibody
Anti-F-Actin Cross-Linking Protein antibody
Anti-ACTN2 antibody

Information sourced from Uniprot.org

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