Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-SAR1B/SARA2 (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
ELISA-antibody detection limit dilution 1:8000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
SAR1B |
Gene ID: |
51128 |
Uniprot ID: |
SAR1B_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_001028675.1; NP_057187.1 |
Specificity: |
Both reported variants (NP_001028675.1 and NP_057187.1) represent identical protein |
Immunogen Sequence: |
DHERLLESKEELD |
Function | GTP-binding protein involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex. Synergizes with the cargo receptor SURF4 to mediate the export of lipoproteins from the endoplasmic reticulum, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis. |
Protein Name | Gtp-Binding Protein Sar1bGtp-Binding Protein BGtbpb |
Database Links | Reactome: R-HSA-1655829Reactome: R-HSA-204005Reactome: R-HSA-2132295Reactome: R-HSA-5694530Reactome: R-HSA-8963888Reactome: R-HSA-9705671Reactome: R-HSA-983170 |
Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinGolgi ApparatusGolgi Stack MembraneAssociated With The Endoplasmic Reticulum And Golgi StacksIn Particular In The Juxta-Nuclear Golgi Region |
Alternative Antibody Names | Anti-Gtp-Binding Protein Sar1b antibodyAnti-Gtp-Binding Protein B antibodyAnti-Gtbpb antibodyAnti-SAR1B antibodyAnti-SARA2 antibodyAnti-SARB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance