Tissue Specificity | Widely expressed. Very low levels are detected in skeletal muscle. Not detected in brain. Down-regulated in aggressive fibromatosis, as well as in breast and colon cancers. Up-regulated in fibroblasts from patients with normophosphatemic tumoral calcinosis (NFTC). |
Function | Double-stranded nucleic acid binding that acts as an antiviral factor by playing an essential role in the formation of cytoplasmic antiviral granules. May play a role in the inflammatory response to tissue injury and the control of extra-osseous calcification, acting as a downstream target of TNF-alpha signaling. Involved in the regulation of EGR1, in coordination with RGL2. May be involved in endosome fusion. |
Protein Name | Sterile Alpha Motif Domain-Containing Protein 9Sam Domain-Containing Protein 9 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Sterile Alpha Motif Domain-Containing Protein 9 antibodyAnti-Sam Domain-Containing Protein 9 antibodyAnti-SAMD9 antibodyAnti-C7orf5 antibodyAnti-DRIF1 antibodyAnti-KIAA2004 antibodyAnti-OEF1 antibody |
Information sourced from Uniprot.org