| Short Description : | Mouse monoclonal anti-Sal-like protein 4 (700-800 aa) for use in IHC, IF and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF/WB |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | ABT-SALL4 |
| Isotype: | IgG2bk |
| Conjugation: | Unconjugated |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:50-100IF 1:50-100WB 1:100-1000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SALL4 |
| Gene ID: | 57167 |
| Uniprot ID: | SALL4_HUMAN |
| Immunogen: | Synthesized peptide derived from the human SALL4 at the amino acid range 700-800 |
| Immunogen Region: | 700-800 aa |
| Specificity: | This antibody detects endogenous levels of human SALL4. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section |
| Post Translational Modifications | Isoform SALL4B exists primarily as a ubiquitinated form. Sumoylation with both SUMO1 and SUMO2 regulates the stability, subcellular localization, transcriptional activity, and may reduce interaction with POU5F1/OCT4. |
| Function | Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells. |
| Protein Name | Sal-Like Protein 4Zinc Finger Protein 797Zinc Finger Protein Sall4 |
| Database Links | Reactome: R-HSA-2892247Reactome: R-HSA-452723Reactome: R-HSA-8943724 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Sal-Like Protein 4 antibodyAnti-Zinc Finger Protein 797 antibodyAnti-Zinc Finger Protein Sall4 antibodyAnti-SALL4 antibodyAnti-ZNF797 antibody |
Information sourced from Uniprot.org
