| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SALL4 |
| Gene ID: | 57167 |
| Uniprot ID: | SALL4_HUMAN |
| Immunogen Region: | 1-220 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human Sall4 (NP_065169.1). |
| Immunogen Sequence: | MSRRKQAKPQHINSEEDQGE QQPQQQTPEFADAAPAAPAA GELGAPVNHPGNDEVASEDE ATVKRLRREETHVCEKCCAE FFSISEFLEHKKNCTKNPPV LIMNDSEGPVPSEDFSGAVL SHQPTSPGSKDCHRENGGSS EDMKEKPDAESVVYLKTETA LPPTPQDISYLAKGKVANTN VTLQALRGTKVAVNQRSADA LPAPVPGANSIPWVLEQILC |
| Tissue Specificity | Expressed in testis. Constitutively expressed in acute myeloid leukemia (AML). |
| Post Translational Modifications | Isoform SALL4B exists primarily as a ubiquitinated form. Sumoylation with both SUMO1 and SUMO2 regulates the stability, subcellular localization, transcriptional activity, and may reduce interaction with POU5F1/OCT4. |
| Function | Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells. |
| Protein Name | Sal-Like Protein 4Zinc Finger Protein 797Zinc Finger Protein Sall4 |
| Database Links | Reactome: R-HSA-2892247Reactome: R-HSA-452723Reactome: R-HSA-8943724 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Sal-Like Protein 4 antibodyAnti-Zinc Finger Protein 797 antibodyAnti-Zinc Finger Protein Sall4 antibodyAnti-SALL4 antibodyAnti-ZNF797 antibody |
Information sourced from Uniprot.org