| Host: | Rabbit |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-SALL4 (1-185aa) is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ZR276 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:100-200 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | SALL4 |
| Gene ID: | 57167 |
| Uniprot ID: | SALL4_HUMAN |
| Immunogen Region: | 1-185aa |
| Specificity: | Positive control: Seminoma |
| Immunogen: | Recombinant fragment (around aa1-185) of human MIC2 protein (exact sequence is proprietary) |
| Tissue Specificity | Expressed in testis. Constitutively expressed in acute myeloid leukemia (AML). |
| Post Translational Modifications | Isoform SALL4B exists primarily as a ubiquitinated form. Sumoylation with both SUMO1 and SUMO2 regulates the stability, subcellular localization, transcriptional activity, and may reduce interaction with POU5F1/OCT4. |
| Function | Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells. |
| Protein Name | Sal-Like Protein 4Zinc Finger Protein 797Zinc Finger Protein Sall4 |
| Database Links | Reactome: R-HSA-2892247Reactome: R-HSA-452723Reactome: R-HSA-8943724 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Sal-Like Protein 4 antibodyAnti-Zinc Finger Protein 797 antibodyAnti-Zinc Finger Protein Sall4 antibodyAnti-SALL4 antibodyAnti-ZNF797 antibody |
Information sourced from Uniprot.org
