Anti-SAFB2 antibody (1-255) (STJ25439)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SAFB2 (1-255) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SAFB2 |
| Gene ID | 9667 |
| Uniprot ID | SAFB2_HUMAN |
| Immunogen Region | 1-255 |
| Immunogen Sequence | MAETLPGSGDSGPGTASLGP GVAETGTRRLSELRVIDLRA ELKKRNLDTGGNKSVLMERL KKAVKEEGQDPDEIGIELEA TSKKSAKRCVKGLKMEEEGT EDNGLEDDSRDGQEDMEASL ENLQNMGMMDMSVLDETEVA NSSAPDFGEDGTDGLLDSFC DSKEYVAAQLRQLPAQPPEH AVDGEGFKNTLETSSLNFKV TPDIEESLLEPENEKILDIL GETCKSEPVKEESSELEQP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human SAFB2 (NP_055464.1). |
Additional Info
| Tissue Specificity | Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines. |
| Function | Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation. |
| Protein Name | Scaffold Attachment Factor B2Saf-B2 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Scaffold Attachment Factor B2 antibodyAnti-Saf-B2 antibodyAnti-SAFB2 antibodyAnti-KIAA0138 antibody |
Information sourced from Uniprot.org