| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Sphingosine 1-phosphate receptor 3 (115-164 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | S1PR3 |
| Gene ID: | 1903 |
| Uniprot ID: | S1PR3_HUMAN |
| Immunogen Region: | 115-164 aa |
| Specificity: | EDG-3 Polyclonal Antibody detects endogenous levels of EDG-3 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human EDG3 at the amino acid range 115-164 |
| Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. |
| Protein Name | Sphingosine 1-Phosphate Receptor 3S1p Receptor 3S1p3Endothelial Differentiation G-Protein Coupled Receptor 3Sphingosine 1-Phosphate Receptor Edg-3S1p Receptor Edg-3 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-419408Reactome: R-HSA-9009391 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 3 antibodyAnti-S1p Receptor 3 antibodyAnti-S1p3 antibodyAnti-Endothelial Differentiation G-Protein Coupled Receptor 3 antibodyAnti-Sphingosine 1-Phosphate Receptor Edg-3 antibodyAnti-S1p Receptor Edg-3 antibodyAnti-S1PR3 antibodyAnti-C9orf108 antibodyAnti-C9orf47 antibodyAnti-EDG3 antibody |
Information sourced from Uniprot.org