Western blot analysis of mouse heart, using S1PR2 antibody (STJ11100163) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-S1PR2 antibody (250-353) (STJ11100163)

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STJ11100163
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: S1PR2
Gene ID: 9294
Uniprot ID: S1PR2_HUMAN
Immunogen Region: 250-353
Specificity: A synthetic peptide corresponding to a sequence within amino acids 250-353 of human S1PR2 (NP_004221.3).
Immunogen Sequence: FSILLLDYACPVHSCPILYK AHYFFAVSTLNSLLNPVIYT WRSRDLRREVLRPLQCWRPG VGVQGRRRGGTPGHHLLPLR SSSSLERGMHMPTSPTFLEG NTVV
Function Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Receptor for the chemokine-like protein FAM19A5. Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration.
Protein Name Sphingosine 1-Phosphate Receptor 2
S1p Receptor 2
S1p2
Endothelial Differentiation G-Protein Coupled Receptor 5
Sphingosine 1-Phosphate Receptor Edg-5
S1p Receptor Edg-5
Database Links Reactome: R-HSA-418594
Reactome: R-HSA-419408
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Sphingosine 1-Phosphate Receptor 2 antibody
Anti-S1p Receptor 2 antibody
Anti-S1p2 antibody
Anti-Endothelial Differentiation G-Protein Coupled Receptor 5 antibody
Anti-Sphingosine 1-Phosphate Receptor Edg-5 antibody
Anti-S1p Receptor Edg-5 antibody
Anti-S1PR2 antibody
Anti-EDG5 antibody

Information sourced from Uniprot.org

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