| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-S1PR2 (250-353) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
S1PR2 |
| Gene ID: |
9294 |
| Uniprot ID: |
S1PR2_HUMAN |
| Immunogen Region: |
250-353 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 250-353 of human S1PR2 (NP_004221.3). |
| Immunogen Sequence: |
FSILLLDYACPVHSCPILYK AHYFFAVSTLNSLLNPVIYT WRSRDLRREVLRPLQCWRPG VGVQGRRRGGTPGHHLLPLR SSSSLERGMHMPTSPTFLEG NTVV |
| Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Receptor for the chemokine-like protein FAM19A5. Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration. |
| Protein Name | Sphingosine 1-Phosphate Receptor 2S1p Receptor 2S1p2Endothelial Differentiation G-Protein Coupled Receptor 5Sphingosine 1-Phosphate Receptor Edg-5S1p Receptor Edg-5 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-419408 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 2 antibodyAnti-S1p Receptor 2 antibodyAnti-S1p2 antibodyAnti-Endothelial Differentiation G-Protein Coupled Receptor 5 antibodyAnti-Sphingosine 1-Phosphate Receptor Edg-5 antibodyAnti-S1p Receptor Edg-5 antibodyAnti-S1PR2 antibodyAnti-EDG5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
