Anti-S100P antibody (1-95) (STJ116980)

Name: Anti-S100P antibody (1-95) (STJ116980)
SKU: STJ116980
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ116980

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Short Description	Rabbit polyclonal S100P (1-95) antibody for use in WB, IHC-P, IF, ICC, IP and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/IP/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:100-1:200 IF/ICC:1:50-1:200 IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	S100P
Gene ID	6286
Uniprot ID	S100P_HUMAN
Immunogen Region	1-95
Immunogen Sequence	MTELETAMGMIIDVFSRYSG SEGSTQTLTKGELKVLMEKE LPGFLQSGKDKDAVDKLLKD LDANGDAQVDFSEFIVFVAA ITSACHKYFEKAGLK
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-95 of human S100P (NP_005971.1).

Tissue Specificity	Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.
Function	May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).
Protein Name	Protein S100-P Migration-Inducing Gene 9 Protein Mig9 Protein S100-E S100 Calcium-Binding Protein P
Database Links	Reactome: R-HSA-6798695
Cellular Localisation	Nucleus Cytoplasm Cell Projection Microvillus Membrane Colocalizes With S100pbp In The Nucleus Colocalizes With Ezr In The Microvilli In A Calcium-Dependent Manner
Alternative Antibody Names	Anti-Protein S100-P antibody Anti-Migration-Inducing Gene 9 Protein antibody Anti-Mig9 antibody Anti-Protein S100-E antibody Anti-S100 Calcium-Binding Protein P antibody Anti-S100P antibody Anti-S100E antibody

Information sourced from Uniprot.org