| Host: | Mouse |
| Applications: | IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Protein S100-A6 (50-90 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ABT-S100A6 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:100-500IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | S100A6 |
| Gene ID: | 6277 |
| Uniprot ID: | S10A6_HUMAN |
| Immunogen Region: | 50-90 aa |
| Specificity: | This antibody detects endogenous levels of human S100A6. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section. The antibody was |
| Immunogen: | Synthesized peptide derived from the human S100A6 at the amino acid range 50-90 |
| Function | May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. |
| Protein Name | Protein S100-A6CalcyclinGrowth Factor-Inducible Protein 2a9Mln 4Prolactin Receptor-Associated ProteinPraS100 Calcium-Binding Protein A6 |
| Cellular Localisation | Nucleus EnvelopeCytoplasmCell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Protein S100-A6 antibodyAnti-Calcyclin antibodyAnti-Growth Factor-Inducible Protein 2a9 antibodyAnti-Mln 4 antibodyAnti-Prolactin Receptor-Associated Protein antibodyAnti-Pra antibodyAnti-S100 Calcium-Binding Protein A6 antibodyAnti-S100A6 antibodyAnti-CACY antibody |
Information sourced from Uniprot.org
![Western blot analysis of various lysates using [KO Validated] S100A6 Rabbit polyclonal antibody (STJ25432) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/100473/386998/STJ25432_1__96427.1713156179.jpg?c=1 "Western blot analysis of various lysates using [KO Validated] S100A6 Rabbit polyclonal antibody (STJ25432) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.")
![Anti-S100A6 antibody [SM5011] (STJA0005011)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/180074/403344/STJA0005011_1__26447.1738950411.png?c=1 "Anti-S100A6 antibody [SM5011] (STJA0005011)")
