| Host: |
Rabbit |
| Applications: |
IHC-P/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
SRM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
IHC-P:1:200-1:800ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
RXRB |
| Gene ID: |
6257 |
| Uniprot ID: |
RXRB_HUMAN |
| Immunogen Region: |
1-100 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RXRB (NP_068811.1). |
| Immunogen Sequence: |
MSWAARPPFLPQRHAAGQCG PVGVRKEMHCGVASRWRRRR PWLDPAAAAAAAVAGGEQQT PEPEPGEAGRDGMGDSGRDS RSPDSSSPNPLPQGVPPPSP |
| Tissue Specificity | Expressed in aortic endothelial cells (at protein level). Expressed in monocytes. Expressed in a variety of tumor cell lines. |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE). |
| Protein Name | Retinoic Acid Receptor Rxr-BetaNuclear Receptor Subfamily 2 Group B Member 2Retinoid X Receptor Beta |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-383280Reactome: R-HSA-5362517Reactome: R-HSA-9029558Reactome: R-HSA-9029569Reactome: R-HSA-9031525Reactome: R-HSA-9031528Reactome: R-HSA-9623433Reactome: R-HSA-9632974 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Rxr-Beta antibodyAnti-Nuclear Receptor Subfamily 2 Group B Member 2 antibodyAnti-Retinoid X Receptor Beta antibodyAnti-RXRB antibodyAnti-NR2B2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
