Anti-RTRAF antibody (29-79) (STJA0006561)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human CN166 AA range: 29-79
General Information
| Short Description | Rabbit polyclonal anti-RNA transcription, translation and transport factor protein (29-79) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RTRAF |
| Gene ID | 51637 |
| Uniprot ID | RTRAF_HUMAN |
| Immunogen | Synthesized peptide derived from human CN166 AA range: 29-79 |
| Immunogen Region | 29-79 |
| Specificity | This antibody detects endogenous levels of human CN166 |
Additional Info
| Function | RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Component of the tRNA-splicing ligase complex and is required for tRNA ligation. May be required for RNA transport. (Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication. |
| Protein Name | Rna Transcription - Translation And Transport Factor ProteinCle7 HomologCleHcle |
| Database Links | Reactome: R-HSA-6784531 |
| Cellular Localisation | NucleusCytoplasmCytosolPerinuclear RegionCytoskeletonMicrotubule Organizing CenterCentrosomeMay Localize At The Centrosome During MitosisShuttles Between The Cytosol And The Nucleus: Enters Into The Nucleus In Case Of Active Transcription While It Accumulates In Cytosol When Transcription Level Is Low(Microbial Infection) Following Influenza A Virus (Iav) InfectionIncluded In Influenza A Virions Via Its Association With Packaged Viral Ribonucleoproteins (Vrnp) In The Nucleus And Cytoplasm |
| Alternative Antibody Names | Anti-Rna Transcription - Translation And Transport Factor Protein antibodyAnti-Cle7 Homolog antibodyAnti-Cle antibodyAnti-Hcle antibodyAnti-RTRAF antibodyAnti-C14orf166 antibodyAnti-CGI-99 antibody |
Information sourced from Uniprot.org